Tupuseleiamides and basiliskamides, new acyldipeptides and antifungal polyketides produced in culture by a Bacillus laterosporus isolate obtained from a tropical marine habitat.
نویسندگان
چکیده
Laboratory cultures of PNG 276, a Bacillus laterosporus isolate obtained from coastal waters off Papua New Guinea, have been shown to produce the novel metabolites basiliskamide A (1), basiliskamide B (2), tupuseleiamide A (3), and tupusleiamide B (4). The structures of 1 to 4 were elucidated by analysis of spectroscopic data and chemical degradation. Basiliskamides A (1) and B (2) show potent in vitro anti-Candida activity.
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ورودعنوان ژورنال:
- Journal of natural products
دوره 65 10 شماره
صفحات -
تاریخ انتشار 2002